Thursday, October 25, 2012

Dr Dracula: Young blood might regenerate cells

IT might sound like something from Dracula, but old brains have been made sprightly again thanks to young blood.
Giving ageing mice blood from much younger animals rejuvenated connections between brain cells and improved memory, experiments have shown.

The treatment is so effective that 18-month-old animals did as well in memory tests as those of only four months. Mice usually live to between 18 months and two years.

If the treatment is shown to be safe and as successful in humans, it could be used to stave off the ravages of old age.

Those in middle-age could be given regular jabs of blood donated by 20-somethings, a conference heard. Diseases such as Alzheimer's could also be held at bay. Researcher Saul Villeda told the Society for Neuroscience's annual conference in New Orleans: 'Do I think that giving young blood could have an effect on a human? I'm thinking more and more that it might.


'It's not a drug that will have deleterious effects. It's just blood. We do it all the time for blood transfusions.'

Scientists from Stanford University in the US 'sewed together' two mice of different ages.

They created connections between their veins and arteries that allowed young blood to flow into the older animal's body, and vice versa. The younger animals' brains appeared to age. But in the older animals, young blood boosted the number of connections between brain cells. The connections, which are thought to be vital to memory, were also stronger.

The older mice also did just as well as the younger ones in memory tests. The treatment is now being tested on mice with an Alzheimer's-like disease. Experts said that if the research continues to bear fruit, it could lead to treatment that brings even greater benefits than penicillin.

Other work suggests an infusion of young blood could be good for the muscles, liver and immune system. However, the work is at an early stage and it will be some time before it is tested on humans.

It may be possible to identify the compounds in blood that are rejuvenating the brain and turn them into a pill.

Professor Andrew Randall, a brain disease expert from Exeter and Bristol Universities, said: 'Although this may suggest that Dracula author Bram Stoker had ideas way ahead of his time, temporarily plumbing teenagers' blood supplies into those of their great-grandparents does not seem a particularly feasible future therapy for cognitive decline in ageing.

'Instead this fascinating work suggests there may be significant benefit in working out what the "good stuff" is in the high octane young blood, so that we can provide just those key components to the elderly.'

Professor Chris Mason, an expert in regenerative medicine from University College London, added: 'The important questions are; what is in the blood of the younger mice that impacts the ageing process, and is it applicable to humans?

'Even if the finding leads only to a drug that prevents, rather than reverses the normal effects of ageing on the brain, the impact upon future generation will be substantial – potentially outweighing other wonder drugs such as penicillin.'

Dr Villeda said: 'Our findings open the possibility of utilising young blood towards future therapeutic interventions aimed at reversing cognitive impairments in the elderly.

'It now becomes a promising prospect to test whether this extends beyond normal ageing towards reversing cellular and cognitive decline in those suffering from age-related neurodegenerative disorders such as Alzheimer's disease.'


http://www.couriermail.com.au/news/dr-dracula-young-blood-might-regenerate-cells/story-e6frep26-1226498792475

Lack of evidence to back up wind turbine sickness

Transcript

Robyn Williams: Evidence: the essence of good science. But many misinterpret what it means. Simon Chapman has written about this problem in connection with wind technology, most recently in New Scientist magazine. And here he is for The Science Show on RN.
Simon Chapman: New technology has long attracted concerns about modern health worries. Microwave ovens, televisions, computer screens, and even early telephony in the late 19th century all caused health anxiety. More recently mobile phones and towers, wi-fi, and smart electricity meters have attracted virulent opposition focused on health problems.
In January I started collecting health claims attributed to wind turbine exposure. Within hours I'd found 50 often florid assertions about different conditions in humans and animals. Today my total sits at 198, with a range redolent of Old Testament plagues and pestilences. The list includes, and I quote: deaths (yes, many deaths, none of which have ever come to the attention of a coroner), various cancers, congenital malformations, and every manner of mental health problem.
But mostly it includes common health problems found in all communities, whether they have wind turbines or not. These include greying hair, energy loss, concentration lapses, weight gain and loss, and all the problems of ageing, the banalities of the human condition.
Sleep problems are most mentioned, but a third of the population suffers from insomnia, so no surprises there. Chickens won't lay near wind farms. Tell that the Tasmanian poultry farmer who has a turbine on site. Earthworms vanish from the soil in an 18-kilometre radius, hundreds of cattle and goats die horrible deaths from 'stray electricity', but veterinary officials are mysteriously never summonsed.
In 35 years in public health I have never encountered anything remotely as apocalyptic. I visited wind farms and compared their gentle swoosh to the noises that all city dwellers live with daily. Quickly this phenomenon began to tick all the psychogenic boxes. There are several reasons to suspect the unrecognised entity of wind turbine syndrome is psychogenic, a communicated disease spread by anti-wind interest groups, sometimes with connections to fossil fuel interests.
Wind farms first appeared about 20 years ago in the USA and have rapidly proliferated. There are now just shy of 200,000 turbines around the world, but the first recorded claims about diseases occurred a decade later when two rural doctors in Wales and Victoria made widely repeated claims that have never been published in any research journal. Turbines are said to cause both chronic conditions like, amazingly, lung and skin cancer, diabetes, multiple sclerosis and stroke, but importantly also acute symptoms. According to Australia's high priestess of wind turbine syndrome, Sarah Laurie, an unregistered doctor, these can commence within 20 minutes of exposure. If this was true, what happened in the early complaint-free years? Where are all the reports of sick people from the 1990s through to 2008 when the claims really took off?
An incredulous European wind industry sees the phenomenon as largely Anglophone, and even then it seems to only occur in particular regions and around certain farms and involve a small fraction of residents. Many wind farms have operated for years and never received a single complaint. Others, legendary for their vocal opponents even before the turbines commenced, are hotbeds of disease claims. So if turbines were intrinsically noxious, why do they cut such a selective disease path? Why do citizens of community owned turbines in places like Germany and Denmark rarely complain? Why are complaints unknown in Western Australia where wind farms have operated for many years, but virulent in several small eastern Australian communities?
Opponents readily concede that only a minority of those exposed report being ill, and explain this via the analogy of motion sickness; it only happens to those who are susceptible. How then to explain that whole regions and indeed nations have no susceptible residents? The key factor seems to be the presence or absence of anti-wind activists, generally visiting from outside the area. Farms with years of community acceptance can erupt with complaints when anti-wind activists arrive in town, spreading alarm and rolling out their laundry list of common health problems they insist are caused by turbines. Prominent among these in Australia are wealthy conservative landowners, appalled by the very visible presence of the tall green energy totems, a constant reminder of bucolic decay and the upstairs-downstairs disdain that they have for those needing the extra income from their often hilly, poorer quality land.
Indeed, money seems to be the magic antidote to the problem. Health complaints are rare among turbine hosts and from those financially benefiting from communal ownership arrangements. In Australia, depending upon the energy generated, a turbine can earn a host between $7,000 and $18,000 a year. Hosts speak of drought proofing their farms when several turbines are hosted. Health complainants tend to be neighbours who can see the turbines, don't like them, and dwell on their misfortune. The perceived injustice can eat away at some and become a preoccupation fermented by organised groups.
Wind companies report of residents approaching them with extensive renovation wish lists. One company told me of a request for a house to be removed to a lake shore, with a jetty thrown in. In rural Australia, residential buyouts from mining companies are common. Word spreads quickly about unsaleable shack owners who got lucky. So when a cashed up company appears in the district, it is understandable that some see their ticket out via protracted complaints.
A recent Canadian case collapsed when the tribunal agreed that complainants should provide their medical records going back 10 years. They refused, saying it would be too difficult to obtain the documentation that every doctor routinely keeps. Opponents claimed that turbine hosts are gagged by confidentiality clauses, so can't speak up about their illnesses. I've seen several contracts and, predictably, none say anything about the hosts shedding their common-law rights to claims of negligence. But the claim persists, with its subtext of ordinary country folk being exploited by fast talking company lawyers.
Apocryphal tales about large numbers of families having to abandon family homes are common. But mysteriously the numbers are never accompanied by address lists. Abandoning unsaleable properties is a sad part of rural decay. Fly in, fly out climate change denialists talk up the tragedy of such communities being ruined by wind farms, but they have no idea about the long-term rural exodus from such economically unviable settlements.
Previous modern health worries dissipated when the predicted health mayhem never eventuated and the feared toxic agents became thoroughly familiar, as they are today throughout much of Europe. Australian hysteria about mobile telephone towers had its heyday in the late 1990s, but is rare today. There are now 17 reviews of the evidence on harm, which are consistent in their assessment of insignificant risk. How long can this latest modern health worry last?
Robyn Williams: At least until the next election, no doubt. Simon Chapman is a professor of public health at the University of Sydney.

http://www.abc.net.au/radionational/programs/scienceshow/the-science-show-20th-october-2012/4316292

Snowtown wind farm to be SA's biggest

Construction is starting to create South Australia's largest wind farm.
It will also be Australia's second biggest.
There will be 90 more turbines added to the Snowtown wind farm, taking the total to 137.
TrustPower said the larger wind farm would be able to generate more than 10 per cent of SA's annual electricity supply.
Chief executive Vince Hawksworth said the new turbines would not have gearboxes and could be quieter than older ones.
"To be fair, all of the ones we've installed we've been very careful about the noise issue, because we know it's a big thing for the community," he said.
"But these wind turbines will be quiet and will certainly be well within all of the noise requirements that our development application requires us to achieve."
Mr Hawksworth said about 200 people would be employed during the construction and operational phases.
The work is due for completion by the end of 2014.
The SA Government said the state had already exceeded Australia's target of producing 20 per cent of its energy from renewable sources by 2020.
It said the additional capacity at Snowtown would help SA achieve its own target of generating 33 per cent of energy from renewable sources by the end of the decade.

http://www.abc.net.au/news/2012-10-25/snowtown-wind-farm-to-be-sas-biggest/4332920

Monday, October 08, 2012

SpaceX sets off on first cargo run

http://www.abc.net.au/reslib/201210/r1015429_11469273.jpg
The Falcon 9 rocket's nine engines lit up the night sky as it launched from Cape Canaveral, Florida (SpaceX)

A private space capsule carrying half a tonne of supplies - including a freezer filled with ice cream - has launched into the night sky above Florida.
Liftoff of the Falcon 9 rocket and Dragon capsule occurred at 11:35 am (AEDT) from Cape Canaveral Air Force Station in Florida.
The company, also known as SpaceX, was founded by internet entrepreneur Elon Musk. It is hoping to restore a US supply line to the station that was cut off by the retirement of the space shuttles last year.
Since then, NASA has been dependent on Russian, European and Japanese freighters to service the station, a permanently staffed research laboratory that flies about 400 kilometres above Earth.
SpaceX is one of two firms hired by NASA to deliver cargo to the station.
Its other contractor, Orbital Sciences Corp, aims to launch its Antares rocket before the end of the year.
Orbital also plans a practice run to the space station, similar to what SpaceX did when its Dragon ship docked at the station.

Reusable spacecraft

For Dragon's first supply run, NASA is sending about 450 kilograms of food, clothing, supplies and science gear to the station.
Unlike previous station cargo ships, which were not reusable and burned up in the atmosphere during descent, SpaceX's capsule returns to Earth.
As a result, it will be able to carry back experiment samples and station hardware that is broken or no longer needed.
The Dragon capsule was expected to reach the station on Wednesday. It would then remain berthed at the outpost for about 18 days and make a parachute descent into the Pacific Ocean two weeks later.

http://www.abc.net.au/reslib/201210/r1015421_11469000.jpg
The Dragon capsule was expected to reach the station on Wednesday (NASA)

Irene Klotz
ABC/Reuters
http://www.abc.net.au/science/articles/2012/10/08/3605875.htm